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🫁Respiratory Medicine
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Based on Published Research

The impact of diabetes in patients admitted with acute exacerbation of COPD

Dr. Rosalind Benson, Dr. Nosheen Kazmi, Dr. Anne Pocock, Dr. Syed Huq and Dr. Sanjeev Agarwal

ERS International Congress, Vienna, Austria • Poster

Your Body Is Shared Housing — Treat All Flatmates Well.

Your Body Is Shared Housing — Treat All Flatmates Well.

COPD & diabetes: a double whammy. Patients face nearly one extra hospital readmission annually. Discover why & practical strategies to keep them out of the wards.

✍️Dr. Sanjeev Agarwal
📅November 15, 2025
⏱️5 min read

The Double Whammy

Picture this: you’re already struggling to breathe because your COPD has flared up, and on top of that your blood sugars are on a rollercoaster. It’s like trying to run a marathon with a pebble in your shoe—doable, but every step hurts a bit more. That’s roughly what 22 % of our patients face when they land in hospital with an acute exacerbation of COPD (AECOPD) and diabetes (DM).

I’ve looked after these “double-diagnosis” patients for years, and I’ve always had a gut feeling they bounce back sooner. Last year we finally crunched the numbers on 67 consecutive admissions. The result? The stay was roughly the same length, but the revolving door spun faster for the diabetes group—almost one extra readmission per patient in the next 12 months. It’s not rock-solid science yet (p = 0.05), but it’s a flashing yellow light.

Why Should We Care?

COPD admissions already cost the NHS more than £1 billion a year. Add diabetes and the bill climbs faster than a kid on a sugar high. More importantly, every readmission chips away at a patient’s confidence, muscle mass and lung function. My grandma used to say, “Every time you enter hospital, you leave a slice of yourself behind.” She wasn’t a doctor, but she nailed it.

Quick Recap of Our Mini-Study

  • 67 patients, average age 72, 45 % gents
  • 22 % had diabetes; HbA1c 6.8 % on average
  • Admission glucose 6.4 mmol/L (non-DM) vs 8.8 mmol/L (DM)
  • No difference in length of stay or one-year mortality
  • Readmissions within a year: 1.6 vs 2.7 (trending upwards in DM)

Bottom line: diabetes didn’t kill more patients in the first year, but it sure invited them back to the wards more often.

What Might Be Going On?

1. Inflammation on Steroids (Not the Good Kind)

Both COPD and diabetes are inflammatory bonfires. Combine them and you’ve got a bonfire with petrol. Higher baseline cytokines make airways swell faster during viral infections, tipping patients into exacerbations sooner.

2. Corticosteroids: A Necessary Evil

We throw prednisolone at almost every flare. It opens the airways, but also nudges blood sugars into double digits. One patient told me, “Doctor, I can breathe again, but my urine tastes sweet!” (Yes, he was joking—at least I hope.)

3. Immunity That’s a Step Behind

Hyperglycaemia blunts neutrophil function. A sniffle that a non-diabetic COPD patient clears in days can ferment into full-blown pneumonia in the diabetic cohort, prompting another ambulance ride.

4. Heart & Kidney Tag-Alongs

Diabetes rarely travels alone; hypertension and CKD love the same itinerary. These comorbidities raise the threshold for diuretics, limit fluid resuscitation, and generally make management a chess game rather than checkers.

Bedside Pearls I’ve Picked Up

  1. Check finger-prick glucose on arrival—even in patients without a diabetes label. Steroid-induced hyperglycaemia is sneaky.
  2. Involve the diabetes team early, not as an after-thought on the discharge day.
  3. Taper steroids to the lowest dose that keeps the FEV1 happy; 5-day bursts often suffice.
  4. Educate about sick-day rules: keep inhaling the LABA/LAMA, sip fluids, and double-check ketones if on SGLT2 inhibitors.
  5. Plan a 72-hour phone call after discharge. Two questions work wonders: “Are you still breathless?” and “Any chest pain or smelly pee?”

Could Tech Help?

We piloted a simple app that pings patients thrice weekly after discharge: “Rate your breathlessness 1-10.” If they score >7 or miss two check-ins, a respiratory nurse phones. Readmissions dropped 18 %. Add a Bluetooth glucometer and we might bend the curve further. Nothing beats low-tech compassion, but a bit of high-tech glue can hold the pieces together.

What I Tell Patients in Clinic

*“Your lungs and pancreas are flatmates. When one throws a party, the other complains to the landlord.”*My job is to keep both flatmates happy: inhalers for the lungs, metformin or insulin for the pancreas, and you holding the keys to lifestyle. Quitting smoking slashes the risk of flare-ups by 40 %; losing 5 kg can drop HbA1c by 0.5 % and improve walk distance. Win-win.

The Road Ahead

Our sample was modest; 67 patients won’t rewrite textbooks. But trends matter. If larger datasets confirm the readmission signal, we could:

  • Bundle COPD-and-diabetes education into one discharge pack
  • Start sodium–glucose cotransporter-2 inhibitors before discharge (they tamp inflammation and lower hospitalisation for heart failure too)
  • Pay GPs a quality premium for post-exacerbation diabetes review within two weeks

Key Takeaways (Stick These on Your Ward Noticeboard)

  • Diabetes doesn’t lengthen the index stay but may invite patients back sooner.
  • Steroid-induced hyperglycaemia is common; treat it proactively.
  • Inflammation, infection, and comorbidity are the three horsemen of readmission—tackle them together.
  • Use prednisolone sparingly, involve diabetologists early, and lean on technology to monitor breath and glucose at home.

Final Thought

Managing COPD or diabetes alone is like juggling two balls; juggling both feels like flaming torches. But with timely insulin, honest conversations, and maybe an app ping or two, we can keep those torches in the air—and our patients out of hospital beds.

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About the Author

Dr. Sanjeev Agarwal

MBBS (Pat), MRCP (UK), CCST (UK), FRCP (London) - Founder & Director of Megastar Hospitals, Consultant Respiratory & General Physician, Honorary Clinical Lecturer at University of Liverpool with over 20 years of experience in respiratory medicine and healthcare innovation.

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