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Based on Published Research

Outcomes of in-hospital adult cardiopulmonary arrest

M. Haris, S. Agarwal, A. Safdar, M.N. Attar, J.G Williams

European Federation of Internal Medicine Congress, Rome, Italy • Spoken

The 'Dil' Dilemma: Why Saving a Heart Starts Before it Stops

The 'Dil' Dilemma: Why Saving a Heart Starts Before it Stops

An analysis of survival rates following in-hospital cardiac arrest, the reality of resuscitation outcomes, and the critical need for better CPR training.

✍️Dr. Sanjeev Agarwal
đź“…December 16, 2025
⏱️6 min read

Introduction

Cardiac arrest has always been an elusive adversary—a nightmare scenario for any medical professional, regardless of their experience level. The sudden cessation of effective circulation strikes at the very core of our duty to preserve life. It is chaotic, high-stakes, and emotionally taxing.

Years ago, during my higher specialist training in respiratory and general medicine in the United Kingdom, I sought to look past the chaos and understand the data behind these events. Along with my colleagues at the North Cheshire Hospitals NHS Trust, I conducted a retrospective, observational study titled "Outcomes of In-Hospital Adult Cardiopulmonary Arrest."

While medical technology has advanced significantly since then, the fundamental lessons from that research remain starkly relevant today. As I reflect on those findings and compare them with my current experiences in India, it becomes clear that while our tools may improve, the philosophy of how we approach cardiac arrest—and more importantly, how we prevent it—needs a unified evolution.

The Research: A Reality Check

The study was designed to evaluate the clinical characteristics and outcomes of adult patients who suffered a cardiopulmonary arrest within the hospital setting and received cardiopulmonary resuscitation (CPR). We analyzed 133 consecutive patients who experienced a total of 143 episodes over a 24-month period.

The demographics were typical of a general hospital population: a mean age of 70 years, with a fairly even split between genders (54% female, 46% male).

The Hard Data

The results were sobering and provided a statistical backbone to what many of us felt clinically:

  • The Nature of the Arrest: The vast majority (93%) were primary cardiopulmonary arrests, while 7% were primary respiratory arrests.
  • Initial Rhythms: On initial assessment, 73% of patients presented with a "non-shockable" rhythm (PEA or asystole), which is generally associated with poorer outcomes compared to shockable rhythms like ventricular fibrillation.
  • Interventions: The medical response was robust. 45% of patients were intubated, 78% received adrenaline, and 60% received atropine. The mean number of CPR cycles was three.

Survival Outcomes

This is where the data speaks loudest. Despite the immediate availability of trained personnel and advanced life support (ALS) drugs:

  • Immediate Success: 37% of patients achieved Return of Spontaneous Circulation (ROSC).
  • Hospital Discharge: Only roughly half of those successfully resuscitated made it out of the hospital (20% of the total cohort).
  • Long-term Survival: The 1-year survival rate stood at just 13%.

Interestingly, there was a significant statistical outlier: patients suffering from primary respiratory arrest had a much higher success rate, with 90% achieving successful resuscitation and a 60% 1-year survival rate. This highlights that when the heart stops due to a lack of oxygen (hypoxia) rather than a primary cardiac failure, reversible interventions are far more effective.

Interpreting the Findings: The Hospital Paradox

Reflecting on this data, there are two critical insights that I believe every healthcare provider—and indeed, patients and their families—must understand.

1. The "Witnessed" Advantage

In our study, 98 episodes were witnessed. Being in a hospital means that when a patient deteriorates, they are usually under surveillance. A witnessed arrest implies that the "down time" (the time without blood flow) is minimized. Monitoring systems trigger alarms, and appropriate interventions—chest compressions, defibrillation, airway management—are initiated almost immediately.

In theory, this should result in high survival rates. However, the data contradicts this assumption.

2. The Limits of Medicine

Despite the "perfect" setting—witnessed events, immediate doctors, advanced drugs, and airway control—the outcomes remain poor. A 13% one-year survival rate tells us that CPR is not a magic wand. By the time a patient's heart stops in a hospital setting (often due to chronic illness, sepsis, or multi-organ failure), the physiological reserve is frequently too depleted to bounce back, even with aggressive resuscitation.

Prevention vs. Cure: A Philosophical Shift

The conclusion of our research was clear: In spite of effective advanced life support training and early identification of critically ill patients, the overall outcome following in-hospital cardiorespiratory arrest remains poor.

This leads to an essential realization in my practice. We must be extremely proactive in treating and handling clinical problems at the earliest stage to avoid a cardiac arrest happening in the first place.

We need to focus on the "pre-arrest" phase. Recognizing the subtle signs of deterioration—a drop in blood pressure, a change in consciousness, a shift in respiratory rate—is infinitely more valuable than being an expert at chest compressions. Once the heart stops, we are fighting a losing battle.

Accepting Mortality

However, we are not gods. There are situations where patients deteriorate despite our best proactive efforts. In these instances, cardiac arrest may represent the natural conclusion of a terminal illness or advanced age.

This brings up the difficult but necessary conversation about futility. Sometimes, aggressive resuscitation on a frail, 90-year-old patient with multiple comorbidities does not extend life; it prolongs the dying process. As a medical community and a society, we have to accept that death is inevitable at a certain stage. Recognizing when resuscitation is futile is as important as knowing how to perform it.

The Challenge in India: A Call for Unified Action

Since moving my practice to India, I have observed a distinct contrast in how cardiac arrests are managed compared to the UK.

In the UK, the National Health Service (NHS) ensures a level of standardization. Every hospital has a "Crash Team," every junior doctor is certified in ALS (Advanced Life Support), and equipment is uniform.

In India, the landscape is fragmented. We have world-class corporate hospitals that rival the best in the West, but we also have a vast network of unorganized small hospitals and nursing homes. Unfortunately, many of these smaller centers are not fully equipped, and not all personnel possess valid certification for dealing with cardiac arrest.

The Knowledge Gap

Furthermore, the Basic Life Support (BLS) and CPR knowledge among the general public in India is extremely poor. In the West, bystanders often initiate CPR before an ambulance arrives, doubling the chances of survival. In India, hesitation and lack of training often lead to precious minutes being lost.

I have been conducting multiple sessions on cardiopulmonary resuscitation and basic life support education for various groups—from medical students to corporate employees. But individual efforts are not enough.

The Way Forward

To improve the outcomes of cardiac arrest in our community, we need a unified approach:

  1. Standardization: Small nursing homes and clinics need access to the same training protocols as large hospitals.
  2. Public Education: CPR training should be as fundamental as learning to drive. It should be taught in schools and workplaces.
  3. Proactive Monitoring: In hospitals, we must double down on "Early Warning Scores" to catch patients before they arrest.

The research I conducted years ago in Cheshire taught me that resuscitation is a desperate, final attempt with low odds. Today, my mission is to improve those odds not just through better resuscitation, but through better prevention, wider education, and a more organized healthcare response.

I will be elaborating on specific aspects of BLS training and the technicalities of respiratory arrest in future posts. For now, let us remember: the best treatment for cardiac arrest is to prevent it from happening.

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About the Author

Dr. Sanjeev Agarwal

MBBS (Pat), MRCP (UK), CCST (UK), FRCP (London) - Founder & Director of Megastar Hospitals, Consultant Respiratory & General Physician, Honorary Clinical Lecturer at University of Liverpool with over 20 years of experience in respiratory medicine and healthcare innovation.

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